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Data in the form of paired (pre-treatment, post-treatment) counts arise in the study of the effects of several treatments after accounting for possible covariate effects. An example of such a data set comes from a dental epidemiological study in Belo Horizonte (the Belo Horizonte caries prevention study) which evaluated various programmes for reducing caries. Also, these data may show extra pairs of zeros than can be accounted for by a simpler model, such as, a bivariate Poisson regression model. In such situations we propose to use a zero-inflated bivariate Poisson regression (ZIBPR) model for the paired (pre-treatment, posttreatment) count data. We develop EM algorithm to obtain maximum likelihood estimates of the parameters of the ZIBPR model. Further, we obtain exact Fisher information matrix of the maximum likelihood estimates of the parameters of the ZIBPR model and develop a procedure for testing treatment effects. The procedure to detect treatment effects based on the ZIBPR model is compared, in terms of size, by simulations, with an earlier procedure using a zero-inflated Poisson regression (ZIPR) model of the post-treatment count with the pre-treatment count treated as a covariate. The procedure based on the ZIBPR model holds level most effectively. A further simulation study indicates good power property of the procedure based on the ZIBPR model. We then compare our analysis, of the decayed, missing and filled teeth (DMFT) index data from the caries prevention study, based on the ZIBPR model with the analysis using a zero-inflated Poisson regression model in which the pre-treatment DMFT index is taken to be a covariate

In recent years there has been an increasing interest in finite projective spaces, and important applications to practical topics such as coding theory, cryptography and design of experiments have made the field even more attractive. In my talk some classical problems and recent developments will be discussed. First I will mention Segre's celebrated theorem and ovals and a purely combinatorial characterization of Hermitian curves in the projective plane over a finite field here, from the beginning, the considered pointset is contained in the projective plane over a finite field. Next, a recent elegant result on semiovals in PG(2,q), due to Gács, will be given. A second approach is where the object is described as an incidence structure satisfying certain properties; here the geometry is not a priori embedded in a projective space. This will be illustrated by a characterization of the classical inversive plane in the odd case. Another quite recent beautiful result in Galois geometry is the discovery of an infinite class of hemisystems of the Hermitian variety in PG(3,q^2), leading to new interesting classes of incidence structures, graphs and codes; before this result, just one example for GF(9), due to Segre, was known.

On homogeneous spaces G/P, where G is a semi-simple Lie group and P is a parabolic subgroup (the ordinary sphere or projective spaces being examples), invariant operators, that is operators between certain homogeneous bundles (functions, vector fields or forms being amongst the typical examples) that are invariant under the action of the group G, have been studied extensively. Especially on so called hermitian symmetric spaces which arise through a 1-grading of the Lie algebra of G there exists a complete classification of first order invariant linear differential operators even on more general manifolds (that allow a so called almost hermitian structure).

This talk will introduce the notion of an invariant bilinear differential pairing between sections of the aforementioned homogeneous bundles. Moreover we will discuss a classification (excluding certain totally degenerate cases) of all first order invariant bilinear differential pairings on manifolds with an almost hermitian symmetric structure. The similarities and connections with the linear operator classification will be highlighted and discussed.

These well-known differential operators are, of course, important in applied mathematics. This is just the tip of an iceberg. I shall indicate some of what lies beneath the surface. There are links with topology, physics, symmetry groups, finite element schemes, and more besides. This talk will touch on these different topics by means of examples. Little prior knowledge will be assumed beyond the equality of mixed partial derivatives.

I will give a historical talk, explaining the steps by which one can deduce Fermat's Last Theorem from a statement about modular forms and elliptic curves.

Enrico Betti (1823-1892) is recognized in the mathematics community for his pioneering contributions to topology. An equally important contribution is his formulation of the reciprocity theorem applicable to elastic bodies that satisfy the classical equations of linear elasticity. Although James Clerk Maxwell (1831-1879) proposed a law of reciprocal displacements and rotations in 1864, the contribution of Betti is acknowledged for its underlying formal mathematical basis and generality. The purpose of this lecture is to illustrate how Betti's reciprocal theorem can be used to full advantage to develop compact analytical results for certain contact and inclusion problems in the classical theory of elasticity. Inclusion problems are encountered in number of areas in applied mechanics ranging from composite materials to geomechanics. In composite materials, the inclusion represents an inhomogeneity that is introduced to increase either the strength or the deformability characteristics of resulting material. In geomechanics, the inclusion represents a constructed material region, such as a ground anchor, that is introduced to provide load transfer from structural systems. Similarly, contact problems have applications to the modelling of the behaviour of indentors used in materials testing to the study of foundations used to distribute loads transmitted from structures. In the study of conventional problems the inclusions and the contact regions are directly loaded and this makes their analysis quite straightforward. When the interaction is induced by loads that are placed exterior to the indentor or inclusion, the direct analysis of the problem becomes inordinately complicated both in terns of formulation of the integral equations and their numerical solution. It is shown by a set of selected examples that the application of Betti's reciprocal theorem leads to the development of exact closed form solutions to what would otherwise be approximate solutions achievable only through the numerical solution of a set of coupled integral equations.

The talk will be the occasion to take a few minutes to describe the situation of math education in France and in Europe, to motivate the interest of the lecturer in trying to bring back rigorous proofs in integration theory. The remaining 45 minutes will be devoted to explaining the basics of Henstock-Kurzweil integration theory, which, although not a response to education problems, is a modern and elementary approach of a very strong extension of the Riemann integral, providing easy access to several fundamental results of Lebesgue theory (monotone convergence theorem, existence of Lebesgue measure, etc.).

Suspension/colloid transport in porous media is a basic phenomenon in environmental, petroleum and chemical engineering. Suspension of particles moves through porous media and particles are captured by straining or attraction. We revise the classical equations for particle mass balance and particle capture kinetics and show its non-realistic behaviour in cases of large dispersion and of flow-free filtration. In order to resolve the paradoxes, the pore-scale model is derived. The model can be transformed to Boltzmann equation with particle distribution over pores. Introduction of sink-source terms into Boltzmann equation results in much more simple calculations if compared with the traditional Chapman-Enskog averaging procedure. Technique of projecting operators in Hilbert space of Fourier images is used. The projection subspace is constructed in a way to avoid dependency of averaged equations on sink-source terms. The averaging results in explicit expressions for particle flux and capture rate. The particle flux expression describes the effect of advective particle velocity decrease if compared with the carrier water velocity due to preferential capture of "slow" particles in small pores. The capture rate kinetics describes capture from either advective or diffusive fluxes. The equations derived exhibit positive advection velocity for any dispersion and particle capture in immobile fluid that resolves the above-mentioned paradox. Finally, we discuss validation of the model for propagation of contaminants in aquifers, for filtration, for potable water production by artesian wells, for formation damage in oilfields.

Noncommutative geometry (in the sense of Alain Connes) involves replacing a conventional space by a "space" in which the algebra of functions is noncommutative. The simplest truly non-trivial noncommutative manifold is the noncommutative 2-torus, whose algebra of functions is also called the irrational rotation algebra. I will discuss a number of recent results on geometric analysis on the noncommutative torus, including the study of nonlinear noncommutative elliptic PDEs (such as the noncommutative harmonic map equation) and noncommutative complex analysis (with noncommutative elliptic functions).

A compact K{\"a}hler manifold $X$ is a holomorphic symplectic manifold if it admits a non-degenerate holomorphic two-form $\sigma$. According to a theorem of Matsushita, fibrations on $X$ must be of a very restricted type: the fibres must be Lagrangian with respect to $\sigma$ and the generic fibre must be a complex torus. Moreover, it is expected that the base of the fibration must be complex projective space, and this has been proved by Hwang when $X$ is projective. The simplest example of these {\em Lagrangian fibrations\/} are elliptic K3 surfaces. In this talk we will explain the role of elliptic K3s in the classification of K3 surfaces, and the (conjectural) generalization to higher dimensions.

The Stein-Tomas restriction theorem says that the Fourier transform of a function in L^p(R^n) restricts to an L^2 function on the unit sphere, for p in some range [1, 2(n+1)/(n+3)]. I will discuss geometric generalizations of this result, by interpreting it as a property of the spectral measure of the Laplace operator on R^n, and then generalizing to the Laplace-Beltrami operator on certain complete Riemannian manifolds. It turns out that dynamical properties of the geodesic flow play a crucial role in determining whether a restriction-type theorem holds for these manifolds.

The ordinary integral on L^1 functions on R^d unfortunately does not extend to a translation invariant linear form on the whole algebra of pseudodifferential symbols on R^d, forcing to work with ordinary linear extensions which fail to be translation invariant. Defect formulae which express the difference between various linear extensions, show that they differ by local terms involving the noncommutative residue. In particular, we shall show how integrals regularised by a "dimensional regularisation" procedure familiar to physicists differ from Hadamard finite part (or "cut-off" regularised) integrals by a residue. When extended to pseudodifferential operators on closed manifolds, these defect formulae express the zeta regularised traces of a differential operator in terms of a residue of its logarithm. In particular, we shall express the index of a Dirac type operator on a closed manifold in terms of a logarithm of a generalized Laplacian, thus giving an a priori local description of the index and shall discuss further applications.

The simple groups are the building blocks of all finite groups. The classification of finite simple groups is a towering achievement of 20th century mathematics. In addition to 18 infinite families of finite simple groups, there are 26 sporadic groups. The biggest sporadic group, dubbed The Monster, has about 10^54 elements. The talk will give a glimpse of this deep area of mathematics.

Berger's classification of irreducibly represented Lie groups that can occur as holonomy groups of semi-Riemannian manifolds is a remarkable result of modern differential geometry. What is remarkable about it is that it is so short and that only so few types of geometry can occur. In Riemannian signature this is even more remarkable, taking into account that any representation of a compact Lie group admits a positive definite invariant scalar product. Hence, for any not too small n there is an abundance of irreducible subgroups of SO(n). We show that in other signatures the situation is quite different with, for example, SO(1,n) having no proper irreducible subgroups. We will show how this and the corresponding result about irreducible subgroups of SO(2,n) follows from the Karpelevich-Mostov theorem. (This is joint work with Antonio J. Di Scala, Politecnico di Torino.)

We define analytic torsion for the twisted de Rham complex, consisting of differential forms on a compact Riemannian manifold X with coefficients in a flat vector bundle E, with a differential given by a flat connection on E plus a closed odd degree differential form on X. The definition in our case is more complicated than in the case discussed by Ray-Singer, as it uses pseudodifferential operators. We show that this analytic torsion is independent of the choice of metrics on X and E, establish some basic functorial properties, and compute it in many examples. We also establish the relationship of an invariant version of analytic torsion for T-dual circle bundles with closed 3-form flux. This is joint work with Siye Wu.

Any matrix in $SL_n (\mathbb C)$ can be written as a product of elementary matrices using the Gauss elimination process. If instead of the field of complex numbers, the entries in the matrix are elements of a more general ring, this becomes a delicate question. In particular, rings of complex-valued functions on a space are interesting cases. A deep result of Suslin gives an affirmative answer for the polynomial ring in $m$ variables in case the size $n$ of the matrix is at least 3. In the topological category, the problem was solved by Thurston and Vaserstein. For holomorphic functions on $\mathbb C^m$, the problem was posed by Gromov in the 1980s. We report on a complete solution to Gromov's problem. A main tool is the Oka-Grauert-Gromov h-principle in complex analysis. Our main theorem can be formulated as follows: In the absence of obvious topological obstructions, the Gauss elimination process can be performed in a way that depends holomorphically on the matrix. This is joint work with Bj\"orn Ivarsson.